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Mentor: Dr. Elena Aikawa

I am a Research Fellow at the Center for Interdisciplinary Cardiovascular Sciences in the Cardiovascular Division of Brigham and Women’s Hospital and Harvard Medical School.

I graduated from McGill University in Montreal, Canada with a major in Chemical Engineering and a minor in Biomedical Engineering and completed my PhD in Biomedical Engineering from the University of Toronto in 2017. There, I was a CIHR Frederick Banting and Charles Best Canada Graduate Scholar and spent time as a Michael Smith Visiting Scholar at the University of California – Irvine. In 2017, my doctoral dissertation on natriuretic peptide signaling in both congenital and acquired aortic valve disease won the John Leyerle-CIFAR Prize for the best interdisciplinary research at the University of Toronto.

Under the mentorship of Dr. Elena Aikawa at CICS, I am using multi-omics and systems biology techniques to identify insights into and treatments for cardiovascular disease. In particular, we are investigating roles for exosomes in mediating vascular/valvular calcification, are studying the molecular bases of congenital calcific aortic valve disease, and developing arrays of 3D-bioprinted, biomechanically relevant models of cardiovascular tissues for high-throughput drug screening.

Keywords

  • Multi-omics
  • Proteomics
  • Calcific aortic valve disease
  • Atherosclerosis
  • Exosomes

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