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Jeffrey M. Hoeg Arteriosclerosis, Thrombosis & Vascular Biology Award

The award recognizes an established investigator in the prime of his or her career who has made an outstanding contribution to furthering understanding of the pathophysiology of atherosclerosis and/or the development of treatment strategies for its prevention through basic science and clinical research efforts. The award honors the memory of Jeffrey M. Hoeg, MD, an extraordinary research scientist and physician who, in the prime of his career, was working in the field of lipoprotein metabolism and atherosclerosis.

2023

Masanori Aikawa, MD, PhD	Professor of Medicine	Email   Aikawa Labs |   CICS*

MASANORI AIKAWA, MD, PhD

2020

Elena Aikawa, MD, PhD

ELENA AIKAWA, MD, PhD, FAHA

Werner Risau Early Career Investigator Award in Vascular Biology

The award was established in honor of Dr. Werner Risau, an investigator who formulated key concepts for the regulation of angiogenesis, challenged the prevailing dogmas about angiogenic factors, and proposed the now accepted hypothesis that several growth factors act sequentially to mediate vasculogenesis, angiogenesis, and vascular remodeling.

The 2023 ATVB Journal Early Career Investigator Award

Arvind Pandey, MD
Instructor in Medicine
Brigham and Women’s Hospital

Expression of CD70 Modulates Nitric Oxide and Redox Status in Endothelial Cells

BWH Cardiovascular Named Fellowships

Each year the BWH Cardiovascular Division honors three outstanding fellowship trainees for their contributions to Cardiovascular Basic Science – Thomas Smith Award, Clinical Science – Eugene Braunwald Award, and Physiology  – Richard Gorlin Award.

The 2023 Honorees for the BWH Cardiovascular Named Fellowships

Richard Gorlin
Award

Intended to promote the investigative career of an individual at the fellow level working in physiology, hemodynamics, or catheterization based research.

Cassandra Clift, PhD

Cassandra L. Clift, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Title: Defining the Histone Code of Epigenetic Regulation in Calcific Aortic Valve Stenosis via Multi-Omics Approaches.
Mentor: Elena Aikawa, MD, PhD

1998 William Maisel, MD
1999 Frederic Resnic, MD
2001 Douglas Drachman, MD
2002 Marc Sabatine, MD
2003 Yerem Yeghiazarians, MD
2004 Akshay Desai, MD
2005 Kent Stephenson, MD
2006 Kevin Croce, MD
2008 Sahil A. Parikh, MD
2009 Reena L. Pande, MD
2010 Matthew Steinhauser, MD
2011 Kumaran Kolandaivelu, MD, PhD
2012 Neil Wimmer, MD
2013 Viviany Taqueti, MD, MPH
2014 Benjamin Galper, MD
2015 Ivana Nikolic, MD
2016 Matthew Nayor, MD
2017 Aaron Kithcart, MD, PhD
2018 Aaron Aday, MD
2019 Sanjay Divakaran, MD
2020 Nicholas Marston, MD
2021 Jenifer M. Brown, MD
2022 Zaid Almarzooq, MB

Eugene Braunwald
Award

Intended to promote the investigative career of an individual at the fellow level working in clinical investigation in the broadest sense.

Aeron Small

Aeron Small, MD
Clinical Fellow in Medicine
Brigham and Women’s Hospital

Title: Genetic and Clinical Determinants of Disease Progression in Calcific Aortic Stenosis.
Mentor: Pradeep Natarajan, MD, MMSc

1998 James Delemos, MD
1999 David Morrow, MD
2001 Koichiro Harada, MD
2002 Thomas Gaziano, MD
2003 Bruce Koplan, MD
2004 Usha Tedrow, MD
2005 Anne Hamik, MD
2006 Benjamin Scirica, MD
2008 Todd S. Perlstein, MD
2009 Jeffrey Winterfield, MD
2010 Paul Cohen, MD
2011 Nathan Stitziel, MD, PhD
2012 Jacob Udell, MD, PhD
2013 Benjamin Olenchock, MD, PhD
2014 Aaron Aguirre, MD, PhD
2015 Kevin King, MD, PhD
2016 Patrick Lawler, MD
2017 Mark Benson, MD, PhD
2018 Arman Qamar, MD
2019 Christopher N. Toepfer, PhD
2020 David D. Berg, MD
2021 Jonathan W. Cunningham, MD
2022 Victor Nauffal, MD

Thomas Smith
Award

Intended to promote the investigative career of a physician at either the fellow or junior faculty level who desires to pursue basic or clinical investigation as it pertains to heart failure.

Eric Wei

Eric Wei, MD, PhD
Clinical Fellow in Medicine
Brigham and Women’s Hospital

Title: In vivo assessment of cardiomyocyte microarchitecture and morphology in genetic heart diseases.
Mentor: Christine Seidman, MD

Previous Award Recipients

1997 Margaret Arstall,MD
1998 Ulrike Mende, MD
1999 Junsuke Igarashi, MD, PhD
2001 Carolyn Ho, MD
2002 Mark W. Feinberg, MD
2003 Marco Lopez-Ilasaca, MD
2004 Paul Christian Schulze, MD
2005 LibinWang, MD, PhD
2006 Jae Kim, MD
2007 Sanjeev A. Francis, MD
2009 Javid Moslehi, MD
2010 Karen Joynt, MD
2011 Bradley A. Maron, MD
2012 Francis Alenghat, MD, PhD
2013 Travis Hinson, MD, PhD
2014 Rajat Gupta, MD
2015 Sunil Kapur, MD
2016 Michael G. Silverman, MD
2017 Kevin Alexander,MD
2018 Andrea Sorrentino, PhD
2019 Rishi K. Wadhera, MD, MPP, MPhil
2020 Daniel Reichart, MD
2021 Brittany Weber, MD, PhD
2022 Deepak Atri, PhD

AHA Career Development Award

Supports highly promising healthcare and academic professionals, in the early years of one’s first professional appointment, to explore innovative questions or pilot studies that will provide preliminary data and training necessary to assure the applicant’s future success as a research scientist.

The American Heart Association recognizes outstanding early career faculty with generous Career Development Awards designed to help launch their careers as they begin their faculty appointment.  The Cardiovascular Division is proud to announce the recipients of the AHA Career Development Award.

2023

Abhijeet Sonawane, PhDInstructor in MedicineEmail   CICS*

Abhijeet Sonawane, PhD
Instructor in Medicine
Brigham and Women’s Hospital

Unraveling Macrophage Heterogeneity using Single-cell Gene Regulatory Networks Approach

Mentors: Elena Aikawa, MD, PhD and Masanori Aikawa, MD, PhD

2021

Brittany N. Weber, MD, PhD Assistant Professor in MedicineEmail*

Brittany Weber, MD, PhD
Instructor in Medicine
Brigham and Women’s Hospital

Advanced CV Imaging and Immunophenotyping to Study Coronary Vascular Health in Psoriasis

Mentor: Marcelo Di Carli, MD

2019

Lai Ming Yung, PhD

Lai Ming Yung, PhD
Instructor in Medicine
Brigham and Women’s Hospital

Biased Agonism of RXFP1 for the Treatment of Pulmonary Arterial Hypertension.

Mentor: Paul B. Yu, MD, PhD

Alan Lerner Research Symposium Award

The Alan Lerner Symposium showcases the breadth and depth of our research enterprise and facilitates our gathering new ideas to pursue for both bench and bedside research. Thank you again for your unwavering support of our young investigators.

2023
Young Investigator Award Recipients, in alphabetical order
David Berg, MD, MPHAssistant Professor of Medicine Email*

David Berg, MD, MPH
Assistant Professor of
Brigham and Women’s Hospital

Assessment of Atherothrombotic Risk in Patients with Type 2 Diabetes Mellitus

Alexander Blood

Alexander J. Blood, MD
Instructor in Medicine
Brigham and Women’s Hospital

Diabetes Remote Intervention to improVe Use of Evidence-Based Medications Study: A Randomized Evaluation of a Team-Based Remote Education and Medication Management Program to Reduce CV and Kidney Risk.

Vivian Lee, PhDInstructor in Medicine	Email*

Vivian Lee, PhD
Instructor in Medicine
Brigham and Women’s Hospital

Variant-to-Function of Coronary Artery Disease: Identifying Novel Regulation of the Notch Pathway in Endothelial Cells

The top three posters from post-doctoral fellows were awarded as follows

FIRST PLACE

Shruti Rawal, PhD
Research Associate in Medicine
Brigham and Women’s Hospital

Regulation of Succinate Signaling and Immunometabolism in Diabetes-associated Atherosclerosis by miR-369-3p

Mentor: Mark W. Feinberg, MD

SECOND PLACE

Three way tie!

Rachel Cahalane, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Searching for the Mechanisms of Accelerated Calcification in Bioprosthetic Heart Valves

Mentor: Elena Aikawa, MD, PhD

Sarvesh Chelvanambi, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

HIV-Nef Extracellular Vesicles Modulate Macrophage Heterogeneity to Promote Atherosclerosis

Mentor: Masanori Aikawa, MD

Shi Fang, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Functional Characterization of a CCM2 Mutation Associated with Coronary Artery Disease

Mentor: Rajat Gupta, MD

THIRD PLACE

Maria A. Pabon MD
Clinical Fellow in Medicine
Brigham and Women’s Hospital

Influence of Background Medical Therapy on Efficacy and Safety of Dapagliflozin in Patients With Heart Failure With Improved Ejection Fraction in the DELIVER Trial

Mentor: Scott D. Solomon, MD

2022
Young Investigator Award Recipients, in alphabetical order
Jonathan W. Cunningham, MD, MPHInstructor in Medicine	Email*

Jonathan W. Cunningham, MD, MPH
Instructor in Medicine
Brigham and Women’s Hospital

Aptamer Proteomics for Biomarker Discovery in Heart Failure with Reduced Ejection Fraction

Laurel Lee

Laurel Y. Lee, MD, DPHIL
Instructor in Medicine
Brigham and Women’s Hospital

T-cell-mediated Endothelial Metabolic Reprogramming in Coronary Artery Disease

Brittany N. Weber, MD, PhD Assistant Professor in MedicineEmail*

Brittany Weber, MD, PhD
Instructor in Medicine
Brigham and Women’s Hospital

Association Between Reduction in Inflammation and Change in Cardiovascular Risk: Results From the LiiRA Study.

2021
Young Investigator Award Recipients, in alphabetical order
Yuri Kim, MD, PhDInstructor in Medicine, HMSAssociate Physician, BWHEmail
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Specialty/interests:

Cardiovascular Genetics
Cardiomyopathy
Genomics
Heart Transplant
Transplant Mechanical Circulatory Support

Yuri Kim, MD, PhD
Instructor in Medicine
Brigham and Women’s Hospital

Intron-Mediated Enhancer of TTN, Encoding Titin, Regulates Sarcomere Formation and Function

Nicholas Marston

Nicholas Marston, MD
Instructor in Medicine
Brigham and Women’s Hospital

Predictive Power and Value of a CAD Polygenic Risk Score in Primary Prevention Based on Age and Clinical Risk

Andriy Samokhin

Andriy Samokhin, PhD
Instructor in Medicine
Brigham and Women’s Hospital

NEDD9 Is a Novel Anti-Fibrotic Therapeutic Target and Biomarker in Pulmonary Arterial Hypertension

The top three posters from post-doctoral fellows were awarded as follows

FIRST PLACE

Jingshu Chen, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Isolation and Primary Culture of Murine Aortic Cells for Atherosclerosis Research

Mentor: Mark W. Feinberg, MD

SECOND PLACE

Rulin Zhuang, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

KLF10 Deficiency in CD4+ T Cells Exacerbate Angiotensin II-Induced Perivascular Fibrosis

Mentor: Mark W. Feinberg, MD

THIRD PLACE

Wandi Zhu, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Piezo1 Mediates a Novel Mechano-Thrombotic Pathway in Cardiometabolic Disease

Mentor: Calum A. MacRae, MD, PhD

2020
Young Investigator Award Recipients, in alphabetical order
Demler Olga

Olga Demler, PhD
Assistant Professor of Medicine
Brigham and Women’s Hospital

Heterogeneous Effects of Omega-3 (n-3) Downstream Fatty Acids (FAs) and Oxylipins on Risk of Cardiovascular Disease: Results of Two Metabolomics Substudies of the Randomized Vitamin D and Omega-3 Trial (VITAL)

Shashi Kant, PhDAssistant Professor of Medicine	skant1@bwh.harvard.edu*

Shashi Kant, PhD
Assistant Professor of Medicine
Brigham and Women’s Hospital

Neural JNK3 Regulates Blood Flow Recovery After Hindlimb Ischemia in Mice via an Egr1/Creb1 Axis

Muthiah Vaduganathan, MD, MPH Instructor in MedicineEmail*

Muthiah Vaduganathan, MD, MPH
Instructor in Medicine
Brigham and Women’s Hospital

Empagliflozin Delays Progression to Insulin Initiation or Intensification in Patients with Type 2 Diabetes and Cardiovascular Disease: Findings from the EMPA-REG OUTCOME Trial

The top three posters from post-doctoral fellows were awarded as follows

FIRST PLACE

Tianxiao Liu

Tianxiao Liu,PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Eosinophils Improve Cardiac Functions After Myocardial Infarction

SECOND PLACE

Liu Xin

Xin Liu,PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Eosinophils Protect Mice From Angiotensin-II Perfusion-Induced Abdominal Aortic Aneurysm

THIRD PLACE

Xian Zhang, PhD

Xian Zhang, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Divergent Roles of Two IL18 Receptors in Brown Adipose Tissue Thermogenesis and White Adipose Tissue Glucose Metabolism and Insulin Sensitivity

 

2019
Young Investigator Award Recipients, in alphabetical order
Rajat Gupta, MD

Rajat Gupta, MD
Assistant Professor of Medicine
Brigham and Women’s Hospital

Single Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations.

Arvind Pandey, MD

Arvind Pandey, MD
Instructor in Medicine
Beth Israel Deaconess Medical Center

CD70 is Essential for Protein Expression in Endothelial Nitric Oxide Synthase.

Sasha Singh, PhD

Sasha Singh, PhD
Instructor in Medicine
Brigham and Women’s Hospital

Insights into Protein Metabolism Heterogeneity Challenge the Reverse Cholesterol Transport Theory: A Novel Mass Spectrometry Platform for Metabolic Tracer Studies in the Clinic

The top three posters from post-doctoral fellows were awarded as follows

FIRST PLACE

Sio (Henry) Cheng, PhD

Sio (Henry) Cheng, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Identification of MicroRNAs in Human and Mouse Diabetic Critical Limb Ischemia.

SECOND PLACE

Patricia Borck, PhD

Patricia Borck, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Inhibition of BRD4 Prevents the Misexpression of Mesenchymal and Fibrotic Markers during Endothelial to Mesenchymal Transition.

THIRD PLACE

Livia Passos, PhD

Livia Passos, PhD
Research Fellow in Medicine
Brigham and Women’s Hospital

Proteins Associated With Sex Hormone Receptor Activity Contribute to Heart Valve Disease.

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