Mentor: Dr. Elena Aikawa
MMy research is focused on understanding of the relationship between inflammatory and vascular/valvular cells, and specialized in multi-OMICs approaches, microscopy, histology, and rodent micro-surgery.
I obtained my PhD degree in Pathophysiology from the University Paul Sabatier of Toulouse (France) under the mentorship of Dr. Muriel Laffargue at the Institute of Cardiovascular and Metabolic Diseases (I2MC). During this period, I studied endothelial healing following vascular injury using methods from in vivo vascular surgery to ex vivo models of endothelial healing. Our findings highlighted novel cellular crosstalk within the arterial wall, whereby a PI3Kγ-dependent T-cell response leads to CXCL10 production by smooth muscle cells and subsequently inhibits endothelial healing.
I joined Dr. Elena Aikawa’s laboratory in 2019 to pursue postdoctoral studies at Center for Excellence in Vascular Biology, Brigham and Women’s Hospital, Harvard Medical School. My work focuses on understanding the roles of the adaptive immune system on cardiovascular calcification, using approaches such as single cell transcriptomic from human tissues and animal models of surgically induced calcification.
Outside of research, I love mountain trail running and road biking.
- Cardiovascular Diseases
- Heart Valve Diseases
- Adaptive immunity